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Image Search Results
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Article Title: Novel BAFF-receptor antibody to natively folded recombinant protein eliminates drug resistant human B-cell malignancies in vivo
doi: 10.1158/1078-0432.CCR-17-1193
Figure Lengend Snippet: (A) Treatment schedule following Day 0 tumor challenge with minimum lethal dose of tumors. Antibody treatments were given by IV tail vein injections: 200 μg treatment antibody, 10 × 106 effector human NK-92-176V cells, and 5 × 104 IU IL-2. Bioluminescence imaging monitored mice challenged with luciferase-expressing tumors: (B) JeKo-1 (MCL) or (C) RS4;11 (ALL). Experimental groups received treatment of chimeric BAFF-R mAbs (C55 or C90, as indicated). Control group mice received PBS, NK cells alone, or rituximab on the same schedule. Data are representative of three independent experiments.
Article Snippet:
Techniques: Imaging, Luciferase, Expressing
Journal: Transplantation and cellular therapy
Article Title: NK Cell Adoptive Immunotherapy of Cancer: Evaluating Recognition Strategies and Overcoming Limitations
doi: 10.1016/j.bbmt.2020.09.030
Figure Lengend Snippet: Sample List of Active Trials Involving Allogeneic NK Cells
Article Snippet: Anderson Cancer Center; National Cancer Institute CB-derived NK cells Rituximab Stem cell transplant Recurrent or refractory B cell non-Hodgkin lymphoma NCT03027128 NantKwest, Inc. NK92 cell line modified to express IL-2 and CD16 (haNK) Metastatic of locally advanced solid tumors NCT03068819 Washington University School of Medicine Cytokine-induced memory-like NK cells CD3 + T cells donor lymphocyte infusion Relapsed AML NCT03136406
Techniques: Transplantation Assay, Modification, Transfection, Expressing, Derivative Assay
Journal: Transplantation and cellular therapy
Article Title: NK Cell Adoptive Immunotherapy of Cancer: Evaluating Recognition Strategies and Overcoming Limitations
doi: 10.1016/j.bbmt.2020.09.030
Figure Lengend Snippet: Sample List of Active Trials Involving Allogeneic NK Cells
Article Snippet: Ospedale Papa Giovanni XXIII Haploidentical cytokine-induced killer cells Relapsed hematologic malignancy after transplant NCT03853317 NantKwest, Inc.; NantCell, Inc. NK92 cell line modified to express IL-2 and CD16 (haNK) Avelumab N-803 Merkel cell carcinoma NCT03937895 SMT bio Co., Ltd. NK cells Pembrolizumab Advanced biliary tract cancer NCT03940833 Asclepius Technology Company Group (Suzhou) Co., Ltd.
Techniques: Transplantation Assay, Modification, Transfection, Expressing, Derivative Assay